Folinic acid CAS 58-05-9

Product Name: Folinic acid
CAS: 58-05-9
MF: C20H23N7O7
MW:473.44
Appearance: Off-white to greenish yellow powder
Assay:97.5% min
Melting point: 245℃
Package: 1kg/Aluminum foil bag

[Specification]

Item	Standard
Appearance	Off-white to greenish yellow powder
Identification	The main peak RT is the same with that of the standard. (by HPLC)
Heavy Metals	≤50ppm
Water content	≤12.0%
Specific optical rotation	+14.5°- +20.5°
Related substances
Individual impurity	≤1.0%
Total impurities	≤2.5%
Purity	≥97.5%

[Usage]

*Calcium folinate is a special form of reduced folate, and high-dose folic acid intervention in children with CFD can improve their neurological and developmental abnormalities. Abnormal folate metabolism is related to the occurrence of autism in children. The genetic polymorphism of folate related pathways may lead to abnormal folate metabolism. A study has found that supplementing with folic acid before childbirth and during pregnancy can reduce the risk of developing autism in offspring.

*Folinic acid (Leucovorin) is a biological folate typically taken in combination with methotrexate (MTX) as a salvage agent to reduce MTX induced toxicity

[Storage]

Keep tightly closed.Store in dry and ventilated place.Keep away from fire,heat sources and oxidants.

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